Jonathan Strange and Mr Norrel by Susanna Clarke: Reviews promised that it had the whimsy and fantasy of the Harry Potter series, with the comedy of manners-style of Austen. At 700+ pages, it had better be good.
Julie and Julia by Julie Powell: I really want to see the movie, but the book looks interesting - I love food memoirs.
The Unlikely Disciple: A Sinner's Semester at America's Holiest University by Kevin Roose: Extremely readable and voyeuristically entertaining. I heard this guy on NPR. A college student from Brown, he tranfers to Liberty University (Jerry Falwell's school) to do an undercover investigation of the religious divide.